Inostamycins B and C, new polyether antibiotics.
نویسندگان
چکیده
منابع مشابه
Noboritomycins A and B, new polyether antibiotics.
Noboritomycins A and B, two new polycyclic ionophoric polyethers were isolated from a strain of Streptomyces noboritoensis. The crystal structure and absolute configuration of noboritomycin A were established by X-ray analysis of its silver salt C43/63O14Ag. Noboritomycin A is the first metabolic polyether possessing two carboxylic acid functions on the carbon backbone (C-31), namely a free aci...
متن کاملOptimization of streptomycete strains producing polyether and macrolide antibiotics.
screened for high-frequency transfer of OTC resistance. Although such strains were found at quite a high frequency (about 1 in IOOO), it was subsequently discovered that a second plasmid SRP2 had actually been primed. This possessed much weaker sex-factor activity than SRPl . Neither plasmid has proved amenable to physical isolation or analysis, and with the advent of recombinant DNA techniques...
متن کاملGalacardins A and B, new glycopeptide antibiotics.
A strain of actinomycetes identified as Saccharothrix sp. SANK 64289 was found to produce new antibiotics, galacardins A and B. Their physico-chemical properties showed that they were new members of glycopeptide antibiotics. They were structurally related to beta-avoparcin but differed from it only in sugar composition. Though beta-avoparcin does not contain galactose, galacardins A and B did c...
متن کاملStructures and Properties of Naturally Occurring Polyether Antibiotics
Polyether ionophores represent a large group of natural, biologically active substances produced by Streptomyces spp. They are lipid soluble and able to transport metal cations across cell membranes. Several of polyether ionophores are widely used as growth promoters in veterinary. Polyether antibiotics show a broad spectrum of bioactivity ranging from antibacterial, antifungal, antiparasitic, ...
متن کامل[Antibiotics from basidiomycetes, VI. Merulinic acids A, B, and C, new antibiotics from Merulius tremellosus and Phlebia radiata (author's transl)].
Three new antibiotics, merulinic acids A, B, and C, have been isolated from fruiting bodies of Merulis tremellosus and Phlebia radiata. They are closely related derivatives of beta-resorcylic and salicylic acid, carrying monounsaturated C17-alkyl side chains in 6-position. The merulinic acids are mixtures of the delta8'-compounds with minor amounts of the corresponding delta10'-, dehydro, and d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1994
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.47.939